1446317-75-4Relevant academic research and scientific papers
Mild copper-mediated direct oxidative cross-coupling of 1,3,4-oxadiazoles with polyfluoroarenes by using dioxygen as oxidant
Zou, Liang-Hua,Mottweiler, Jakob,Priebbenow, Daniel L.,Wang, Jun,Stubenrauch, Jan Alexander,Bolm, Carsten
supporting information, p. 3302 - 3305 (2013/07/05)
CH3CN and O2 do the trick! A copper-mediated direct oxidative cross-coupling of 2-(het)aryl-1,3,4-oxadiazoles with polyhaloarenes under mild reaction conditions has been developed (see scheme). The process provides a concise access to biaryl structures containing polyhaloarenes, which are of interest in the fields of pharmaceuticals and functional materials. Acetonitrile and oxygen play crucial roles. Copyright
