1446320-96-2Relevant academic research and scientific papers
Facile synthesis of pyrido[2,1- a ]isoindoles via iron-mediated 2-arylpyridine C-H bond cleavage
Liu, Shan,Hu, Xingen,Li, Xinhua,Cheng, Jiang
, p. 847 - 850 (2013)
An iron-catalyzed reaction of 2-arylpyridine C-H bond with 2-bromoacetophenone is achieved, providing pyrido[2,1-a]-isoindoles in moderate to good yields. The regioselectivity stems from the domination of hindrance on the regioselective ortho-functionalization of 2-arylpyridines C-H bond. Georg Thieme Verlag Stuttgart · New York.
