4373-58-4

Basic information

• Product Name: Pyridine, 2-(3-methoxyphenyl)-
• CAS NO: 4373-58-4
• Molecular Formula: C12H11NO
• Molecular Weight: 185.225
• Mol File: 4373-58-4.mol
• Article Data: 77

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(3-methoxyphenyl)-(4373-58-4)
• EPA Substance Registry System: Pyridine, 2-(3-methoxyphenyl)-(4373-58-4)

Safety Data

• Hazardous Substances Data: 4373-58-4(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 100-66-3 methoxybenzene 
• 2398-37-0 3-methoxyphenyl bromide 
• 109-04-6 2-bromo-pyridine 
• 107099-99-0 2,5-dimethoxyphenylboronic acid 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 98061-26-8 2-(2,5-dimethoxyphenyl)pyridine 
• 628-13-7 pyridine hydrochloride 
• 536-90-3 m-Anisidine 
• 2845-89-8 1-chloro-3-methoxy-benzene 
• 24367-66-6 2-pyridinesulfinic acid sodium salt 
• 197958-29-5 pyridin-2-ylboronic acid 
• 110-86-1 pyridine 
• 1394011-04-1 (4-methoxy-2-(pyridin-2-yl)phenyl)(phenyl)methanol 

Downstream Products

• 854898-06-9 4-methoxy-2-[2]pyridyl-aniline 
• 1064605-09-9 2-(2-cyclooctyl-5methoxyphenyl)pyridine 
• 1421006-83-8 (E)-2-(3-methoxy-2-(2-methylstyryl)phenyl)pyridine 
• 1421006-84-9 (E)-2-(5-methoxy-2-(2-methylstyryl)phenyl)pyridine 
• 1236046-58-4 (4-methoxy-2-(pyridin-2-yl)phenyl)(phenyl)methanone 
• 1443422-62-5 4-methoxy-2-(pyridin-2-yl)benzonitrile 
• 1039045-20-9 2-(2,6-diphenyl-5-methoxyl)-phenylpyridine 
• 1127213-38-0 2-(2,6-divinylphenyl-5-methoxyl)-phenylpyridine 
• 1015758-31-2 ethyl 2-methoxy-6-(pyridin-2-yl)benzoate 

Relevant articles and documents

New aspects of the aromatic photosubstitution with iodopyridines

Reactive entities in the photoreaction of 2-, 3- and 4-iodopyridines with substituted benzenes were investigated; 3- and 4-pyridylation could be explained in terms of radical reaction, while the 2-pyridyl cation was an important intermediate in the 2-pyridylation. The importance of the unshared electron pair of the nitrogen adjacent to the radical carbon for the conversion of the 2-pyridyl radical initially produced into the cation is discussed on the basis of molecular orbital (MO) calculations.

Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C-O Bonds

Reductive cleavage of aromatic and benzylic C-O bonds by chromium catalysis is reported. This deoxygenative reaction was promoted by low-cost CrCl 2precatalyst combined with poly(methyl hydrogen siloxane) as the mild reducing agent, providing a strategy in forming reduced motifs by cleavage of unactivated C-O bonds. A range of functional groups such as bromide, chloride, fluoride, hydroxyl, amino, and alkoxycarbonyl can be retained in the reduction.

Photoarylation of Pyridines Using Aryldiazonium Salts and Visible Light: An EDA Approach

A metal-free methodology for the photoarylation of pyridines, in water, is described giving 2 and 4-arylated-pyridines in yields up to 96percent. The scope of the aryldiazonium salts is presented showing important results depending on the nature and position of the substituent group in the diazonium salt, that is, electron-donating or electron-withdrawing in the ortho, meta, or para positions. Further heteroaromatics were also successfully photoarylated. Mechanistic studies and comparison between our methodology and similar metal-catalyzed procedures are presented, suggesting the occurrence of a visible-light EDA complex which generates the aryl radical with no need for an additional photocatalyst.