1446348-70-4Relevant academic research and scientific papers
A biomimetic approach to the synthesis of terpene-amino acid conjugates. The Ugi reaction in the hypothetical biosynthesis of marine natural products
Ichikawa, Yoshiyasu,Saito, Kenta,Mimura, Rika,Kitamori, Ayumi,Matsukawa, Akihito,Ikeda, Akifumi,Masuda, Toshiya,Kotsuki, Hiyoshizo,Nakano, Keiji
, p. 1040 - 1053 (2016)
A unique pathway for the biosynthesis of the marine sponge terpenes, exigurin and boneratamides A-C, is proposed. Based on this proposal, a biomimetic strategy on key Ugi coupling reactions between terpene isocyanides and amino acids was developed for construction of the core structures of exigurin and boneratamides A-C.
A biomimetic approach to terpenes isolated from marine sponges: A Ugi coupling reaction in a hypothetical biosynthesis
Saito, Kenta,Nishimori, Ayumu,Kotsuki, Hiyoshizo,Nakano, Keiji,Ichikawa, Yoshiyasu
, p. 757 - 761 (2013/05/09)
A unique pathway for the biosynthesis of marine sponge terpenes is proposed. Based on this proposal, a biomimetic approach using a Ugi coupling reaction has been designed and applied to the efficient construction of the right-side, peptide-like portions of boneratamides and exigurin. Georg Thieme Verlag Stuttgart - New York.
