1446355-99-2Relevant academic research and scientific papers
Preparation of chiral key intermediates of morpholine based neurokinin receptor antagonists by asymmetric allylic alkylation
Keldenich, Jér?me,Denicourt-Nowicki, Audrey,Michon, Christophe,Agbossou-Niedercorn, Francine
, p. 6424 - 6430 (2013/07/26)
Abstract The preparation of optically active morpholine-2-aryl-2-allyl derivative from morpholine-2-aryl-3-ones is reported. The optically active tetrasubstituted stereocenter is introduced during a palladium promoted asymmetric allylic alkylation. The re
