1446394-40-6Relevant articles and documents
Organocatalytic asymmetric remote aziridination of 2,4-dienals
Halskov, Kim Soholm,Naicker, Tricia,Jensen, Magnus E.,Jorgensen, Karl Anker
, p. 6382 - 6384 (2013)
Highly regio- and stereoselective remote aziridination of 2,4-dienals has been developed, based on a vinylogous iminium-ion-dienamine catalytic cascade reaction. Transformations of the aziridine products into enantioenriched motifs are also demonstrated. Furthermore, the reaction concept is extended to include enantioselective 1,6-addition of thiols.