14465-68-0

Basic information

• Product Name: TRILINOLENIN
• Synonyms: 9,12,15-Octadecatrienoic acid, 1,2,3-propanetriyl ester, (all-Z)-;1,2,3-TRI-[(CIS,CIS,CIS)-9,12,15-OCTADECATRIENOYL]-GLYCEROL;C18:3,[CIS,CIS,CIS]-9,12,15;GLYCEROL TRILINOLENATE;TRILINOLENIN;Glyceryl trilinolenate;trilinolenin (C18:3,-cis,cis,cis-*9,12,15);trilinolenin (C18:3,cis,cis,cis-9,12,*15) with bh
• CAS NO: 14465-68-0
• Molecular Formula: C₅₇H₉₂O₆
• Molecular Weight: 873.34
• EINECS: 238-457-5
• Mol File: 14465-68-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: -23-24 °C
• Boiling Point: 814.4°Cat760mmHg
• Flash Point: 303.3°C
• Appearance: /liquid
• Density: 0.94 g/mL at 20 °C(lit.)
• Vapor Pressure: 1.33E-26mmHg at 25°C
• Refractive Index: n20/D 1.489
• Storage Temp.: 2-8°C
• BRN: 1718706
• CAS DataBase Reference: TRILINOLENIN(CAS DataBase Reference)
• NIST Chemistry Reference: TRILINOLENIN(14465-68-0)
• EPA Substance Registry System: TRILINOLENIN(14465-68-0)

Safety Data

• F: 10-23
• Hazardous Substances Data: 14465-68-0(Hazardous Substances Data)

Usage

Description

TRILINOLENIN, also known as a triacylglycerol, is a triglyceride formed by the acylation of the three hydroxy groups of glycerol with linolenic acid. It is a naturally occurring compound found in plant oils and is characterized by its unique structure and properties.

Uses

Used in Pharmaceutical Industry:
TRILINOLENIN is used as an active pharmaceutical ingredient for its potential therapeutic applications. The compound's unique structure allows it to interact with various biological targets, making it a promising candidate for the development of new drugs.
Used in Cosmetic Industry:
TRILINOLENIN is used as an ingredient in the cosmetic industry due to its moisturizing and emollient properties. It helps to improve the skin's hydration and texture, making it a valuable component in various skincare products.
Used in Food Industry:
TRILINOLENIN is used as a component in the food industry, particularly in the production of edible oils and fats. Its presence in plant oils contributes to the overall nutritional value and health benefits of these products.
Used in Research and Development:
TRILINOLENIN is used as a research tool in the field of biochemistry and molecular biology. Its unique structure and properties make it an interesting subject for studying the interactions between lipids and other biological molecules, as well as for exploring its potential applications in drug discovery and development.

InChI:InChI=1/C57H92O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h7-12,16-21,25-30,54H,4-6,13-15,22-24,31-53H2,1-3H3/b10-7-,11-8-,12-9-,19-16-,20-17-,21-18-,28-25-,29-26-,30-27-

Upstream product

• 463-40-1 (9Z,12Z,15Z)-octadeca-9-12,15-trienoic acid 
• 56-81-5 glycerol 
• 59044-29-0 cis,cis,cis-9,12,15-octadecatrienoyl chloride 
• 54562-14-0 z,z,z-octadeca-6,9,12-trienoyl chloride 
• 506-26-3 all-cis-6,9,12-octadecatrienoic acid 

Downstream Products

• 55268-58-1 (Z,Z,Z)-linolenic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester 
• 88275-23-4 1,2-dihexadecanoyl-3-(9,12,15-octadecatrienoyl)glycerol 
• 32373-20-9 1,3-dihexadecanoyl-2-(9,12,15-octadecatrienoyl)glycerol 
• 116229-50-6 1,3-dilinolenoyl-2-palmitoylglycerol 
• 106800-94-6 α-Palmitoyl-α',β-dilinolenoin-triglycerid 
• 79925-46-5 2-linolenoyloxy-1,3-bis-linoloyloxy-propane 
• 79925-48-7 LnLnL 
• 55771-89-6 1,2-dilinoleoyl-3-linolenoylglycerol 
• 79925-47-6 tri‐linoleoyl‐sn‐glycerol 
• 2190-25-2 2-Oleodipalmitin 
• 1867-91-0 1,2-dipalmitoyl-3-oleoyl-rac-glycerol 
• 97949-46-7 α-Linoleoyl-β-palmitoyl-α'-oleoin 
• 90318-80-2 (Z,Z,Z)-octadeca-9,12,15-trienoic acid 2,3-bis((Z)-octadec-9-enoyloxy)propyl ester 
• 102282-18-8 1-Oleoyloxy-2,3-bis-α-linolenoyloxy-propan 

Relevant articles and documents

TREATMENT OF NEURODEGENERATIVE CONDITIONS

A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety being selected from the group consisting of γ-linolenic acid, dihomo-γ-linolenic acid and arachidonic acid characterised in that the selected fatty acid moiety is attached to the glycerol moiety at its sn-2 position. Preferably the method is that wherein the lipid is administered for a duration and at a dose sufficient to maintain or elevate TGF-β1 levels in the patient to therapeutic levels.

Fat Hydrolysis and Esterification by a Lipase from Humicola lanuginosa

The hydrolysis and esterification by a thermostable lipase from Humicola lanuginosa No. 3 were investigated.Both reactions occurred readily at temperatures between 45-50 deg C.Esterification by the enzyme with glycerol was observed to be specific towards fatty acids with carbon numbers of C12-C18.Lauric acid esters with different alcohols such as primary alcohols, terpene alcohols, etc., were also synthesized readily.Esterification by the enzyme was adversely affected by the water content (optimum, ca. 7percent), however, the hydrolysis rate increased rapidly with increasing water content (optimum, ca. 60percent).The enzyme showed increased activity in organic solvent-aqueous reaction systems.Nevertheless, hydrolysis in complete organic phase reactions was found not to be feasible.Hydrolysis at a higher temperature (50 or 55 deg C) in a solvent free phase was almost the same as that in organic solvent-aqueous phase reactions.The components of glycerides varied considerably during hydrolysis, whereby esterification resulted in a higher quantity of mono- and diglycerides (about 40percent), compared to in the case of hydrolysis, for which the value was about 10-20percent.