144650-01-1

Basic information

• Product Name: 2,3-DIMETHOXY-BENZAMIDINE
• Synonyms: 2,3-DIMETHOXY-BENZAMIDINE;2,3-dimethoxybenzamidine acetic acid
• CAS NO: 144650-01-1
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.2
• Product Categories: pharmacetical
• Mol File: 144650-01-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 300.1 °C at 760 mmHg
• Flash Point: 135.3 °C
• Appearance: /
• Density: 1.17 g/cm³
• Vapor Pressure: 0.00114mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.44±0.50(Predicted)
• CAS DataBase Reference: 2,3-DIMETHOXY-BENZAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHOXY-BENZAMIDINE(144650-01-1)
• EPA Substance Registry System: 2,3-DIMETHOXY-BENZAMIDINE(144650-01-1)

Safety Data

• Hazardous Substances Data: 144650-01-1(Hazardous Substances Data)

Usage

General Description

2,3-DIMETHOXY-BENZAMIDINE, also known as 2,3-dimethoxybenzamidine or 2,3-DMBA, is a chemical compound with the molecular formula C9H12N2O2. It is a derivative of benzamidine and consists of a benzene ring with two methoxy groups and an amidine functional group. 2,3-DIMETHOXY-BENZAMIDINE is commonly used as a reagent in chemical synthesis and pharmaceutical research, particularly in the synthesis of various organic compounds and pharmaceutical drugs. It exhibits potent antibacterial and antifungal properties, and its structure and properties have made it a subject of interest in medicinal chemistry research. Overall, 2,3-DIMETHOXY-BENZAMIDINE is a versatile compound with various potential applications in chemistry and pharmaceuticals.

InChI:InChI=1/C9H12N2O2/c1-12-7-5-3-4-6(9(10)11)8(7)13-2/h3-5H,1-2H3,(H3,10,11)

Upstream product

• 5653-62-3 2,3-dimethoxybenzonitrile 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 159488-88-7 2-(2,3-dimethoxyphenyl)-4-(hydroxymethyl)imidazole 
• 407610-19-9 2-(2,3-dimethoxyphenyl)imidazole-4-carboxaldehyde 
• 160511-29-5 5-Chloromethyl-2-(2,3-dimethoxy-phenyl)-1H-imidazole 

Relevant articles and documents

Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives: new classes of dopamine receptor subtype specific ligands

Disclosed are compounds of the formula: wherein R1 represents optionally substituted aryl, heteroaryl, arylalkyl, or cycloalkyl groups; X, Z, and Y are optionally substituted nitrogen or carbon atoms; R3 and R4 are organic or inorganic substitutents which may togther form ring structutes; m is zero, one or two; and R5 and R6 are are organic or inorganic substituents; and the pharmaceutically acceptable addition salts thereof, which compounds are highly selective partial agonists or antagonists at brain dopamine receptor subtypes or prodrugs thereof and are useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism.

CERTAIN AMINOMETHYL PHENYLIMIDAZOLE DERIVATIVES; AND 4-ARYL SUBSTITUTED PIPERAZINYL AND PIPERIDINYLMETHYL PHENYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE LIGANDS

This invention encompasses compounds of the formulas: STR1 where R. sub.1 R 3, R 4, R 6, X, Y, and Z are T are variables; andM is STR2 where R 2 is a variable; or R. sub.1 and R. sub.2 together may represent--(CH 2) n1 where n 1 is 1, 2, or 3.P

2-Phenyl-4-(aminomethyl)imidazoles as Potential Antipsychotic Agents. Synthesis and Dopamine D2 Receptor Binding

A series of 2-phenyl-4-(aminomethyl)imidazoles were designed as conformationally restricted analogs of the dopamine D2 selective benzamide antipsychotics.The title compounds were synthesized and tested for blockade of YM-09151 binding in cloned African green monkey dopamine D2 receptor preparations.The binding affinity data thus obtained were compared against that of the benzamides and a previously described series of 2-phenyl-5-(aminomethyl)pyrroles.