144651-59-2

Basic information

• Product Name: 2-Propen-1-one, 1,3-diphenyl-3-(1-pyrrolidinyl)-
• CAS NO: 144651-59-2
• Molecular Formula: C19H19NO
• Molecular Weight: 277.366
• Mol File: 144651-59-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1,3-diphenyl-3-(1-pyrrolidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1,3-diphenyl-3-(1-pyrrolidinyl)-(144651-59-2)
• EPA Substance Registry System: 2-Propen-1-one, 1,3-diphenyl-3-(1-pyrrolidinyl)-(144651-59-2)

Safety Data

• Hazardous Substances Data: 144651-59-2(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 120-46-7 1,3-diphenylpropanedione 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 70-11-1 α-bromoacetophenone 
• 15563-45-8 1-thiobenzoylpyrrolidine 
• 145930-95-6 (2-Oxo-2-phenyl-ethyl)-[1-phenyl-1-pyrrolidin-1-yl-meth-(E)-ylidene]-sulfonium; bromide 
• 85169-79-5 1-(1,3-diphenyl-3-oxo-1-propen-1-yl)-3-methylimidazolium iodide 
• 91860-00-3 3-(1H-imidazol-1-yl)-1,3-diphenylprop-2-en-1-one 

Relevant articles and documents

Easily available nickel complexes as catalysts for the intermolecular hydroamination of alkenes and alkynes

A series of nickel complexes of the type [(P-P)NiX2] ((P-P) = bisphospines or bisphosphites, X = chloride, triflate) were used as catalysts for the hydroamination of both activated and unactivated alkenes and alkynes with pyrrolidine. In general, the use of activated unsaturations, such as acrylonitrile, required mild reaction conditions (e.g. 100 °C and 4 h) in comparison with other non-activated alkenes. Particularly with a series of alkynes, the use of nickel(ii) centers diminished or even inhibited the formation of otherwise undesired homocoupling and/or transfer hydrogenation by-products, such as the ones obtained in the presence of zerovalent nickel. When using less activated substrates, better selectivity was obtained, although harsher reaction conditions were needed. From a general perspective, the results of this report strongly support the potential use of nickel as a good candidate for further application in the hydroamination of organic unsaturations by means of screening of several π acceptor ligands. The Royal Society of Chemistry.

STUDY OF THE ESCHENMOSER SULFIDE CONTRACTION METHOD WITH AND WITHOUT A THIOPHILE

Results obtained and observations made by applying the title method for the synthesis of enaminones 5a-o, using triphenylphosphine as a thiophile and triethylamine as a base, are reported.The product distributions of the deprotonations of α-phenacylthio iminium bromides with and without thiophile and those known from thiouronium and heterocyclic thionium analogs are compared.Key words: Enaminones; α-phenacylthio iminium bromides; disulfides; thiiranes.

TRISUBSTITUTED THIAZOLES BY A 6?-ELECTROCYCLIZATION OF IMINOTHIOCARBONYL YLIDES

Iminothiocarbonyl ylides are generated by a sulfur ligand exchange reaction of sulfonium salts and undergo a 6?-electrocyclic closure and aromatization to tri substituted thiazoles.Related carbonyl ylides preferred a 4?-electrocyclization.