1446516-76-2

Upstream product

• 130336-16-2 3,5-dichloro-2,2,2-trifluoroacetophenone 
• 1446516-75-1 1,3-dichloro-5-(1,1-dibromo-3,3,3-trifluoroprop-1-en-2-yl)benzene 
• 74-88-4 methyl iodide 

Downstream Products

• 1446516-82-0 1,3-dichloro-5-(3,4-dibromo-1,1,1-trifluorobut-2-en-2-yl)benzene 
• 1446516-86-4 1,3-dichloro-5-(3,4-dibromo-1,1,1-trifluorobut-2-en-2-yl)benzene 

Relevant academic research and scientific papers

Ruthenium catalyzed reductive coupling of paraformaldehyde to trifluoromethyl allenes: CF3-bearing all-carbon quaternary centers

Trifluoromethyl substituted allenes engage in ruthenium catalyzed reductive couplings with paraformaldehyde to form products of hydrohydroxymethylation as single regioisomers. This method enables generation of CF3-bearing all-carbon quaternary