144654-43-3

Basic information

• Product Name: 4,10-bis(deacetyl)-7-(triethylsily)baccatin III
• Synonyms: 4,10-bis(deacetyl)-7-(triethylsily)baccatin III
• CAS NO: 144654-43-3
• Molecular Weight: 616.824
• Mol File: 144654-43-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,10-bis(deacetyl)-7-(triethylsily)baccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: 4,10-bis(deacetyl)-7-(triethylsily)baccatin III(144654-43-3)
• EPA Substance Registry System: 4,10-bis(deacetyl)-7-(triethylsily)baccatin III(144654-43-3)

Safety Data

• Hazardous Substances Data: 144654-43-3(Hazardous Substances Data)

Upstream product

• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 
• 115437-21-3 7-(triethylsilyl)baccatin III 

Downstream Products

• 175444-21-0 C₃₃H₄₆O₉Si 
• 160511-43-3 4-deacetyl-7-(triethylsilyl)baccatin III 13-<(4S,5R)-3-(tert-butoxycarbonyl)-5-carboxyl-2,2-dimethyl-4-phenyl-1,3-oxazolidine> 
• 160511-44-4 4-deacetyl-N-debenzoyltaxol 
• 175444-23-2 C₅₅H₇₃NO₁₄Si 
• 175444-20-9 C₃₃H₅₀O₉Si 
• 175444-22-1 C₃₃H₄₈O₉Si 
• 160768-74-1 4,10-bis(deacetyl)-7-triethylsily-13-((4S,5R)-N-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-5-oxazolidinyl)baccatin III 

Relevant articles and documents

Taxoids: 11,12-dihydro-4-deacetyldocetaxel

11,12-dihydro-4-deacetyldocetaxel was prepared from 10-deacetylbaccatin III via its reduced derivative at C11, C12. The title compound is not active in microtubules disassembly.

Rearrangement reactions of taxanes: Structural modifications of 10-deacetylbaccatin III

10-Deacetylbaccatin III 2 is a taxane diterpenoid isolated from the plant genus Taxus, which has been used for the partial synthesis of the antitumor compounds taxol and taxotere. A number of structural modifications have been performed on 2 under acidic