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1446690-25-0

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1446690-25-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1446690-25-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,6,6,9 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1446690-25:
(9*1)+(8*4)+(7*4)+(6*6)+(5*6)+(4*9)+(3*0)+(2*2)+(1*5)=180
180 % 10 = 0
So 1446690-25-0 is a valid CAS Registry Number.

1446690-25-0Relevant articles and documents

Synthesis and biological evaluation of novel pentacyclic triterpene derivatives as potential PPARγ agonists

Zhang, Liying,Dong, Jizhe,Liu, Jun,Zhang, Luyong,Kong, Lingyi,Yao, Hequan,Sun, Hongbin

, p. 118 - 125 (2013/04/23)

Synthesis and biological evaluation of a novel series of substituted pentacyclic triterpene derivatives as potential PPARγ agoinsts and glycogen phosphorylase inhibitors have been described. Compounds 11 and 17 showed potent PPARγ agonistic activity and activated the transcription activity of PPARγ in a dose-dependent manner. On the other hand, eleven compounds exhibited moderate inhibitory activity against rabbit muscle glycogen phosphorylase a (RMGPa), and triterpene 10 was the best one. Structure-activity relationship (SAR) is also discussed.

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