14467-65-3Relevant academic research and scientific papers
Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma
Huang, He,Li, Huiying,Yang, Sun,Chreifi, Georges,Martásek, Pavel,Roman, Linda J.,Meyskens, Frank L.,Poulos, Thomas L.,Silverman, Richard B.
, p. 686 - 700 (2014/03/21)
Selective inhibitors of neuronal nitric oxide synthase (nNOS) are regarded as valuable and powerful agents with therapeutic potential for the treatment of chronic neurodegenerative pathologies and human melanoma. Here, we describe a novel hybrid strategy
Thiophene-2-carboximidamide Based Selective Neuronal Nitric Oxide Inhibitors
-
Paragraph 0030, (2014/03/25)
Selective neuronal nitric oxide synthase (nNOS) inhibitor compounds designed with one or more thiophene-2-carboximidamide substituents for improved bioavailability.
Dipole Moments and UV Spectra of some Long-chain Molecules
Baliah, V.,Aparajithan, K.
, p. 255 - 259 (2007/10/02)
About one hundred compounds with long-chain molecular structure have been prepared (most of them are new).The dipole moments of four α,ω-bis(p-methoxyphenylthio)alkanes and five α,ω-bis(p-methoxyphenylsulphonyl)alkanes have been determined to find the effect of chain-length.In the case of sulphones, the observed values are compared with the values calculated for free rotation around all bonds intervening the end dipoles.The uv spectra of some 1,2-(distyrylsulphonyl)ethanes, and a number of α,ω-bis(arylsulphonyl)- and α,ω-bis(aryloxy)alkanes have been recorded to examine the applicability of the principle of chromophore additivity.
