6245-49-4Relevant academic research and scientific papers
Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma
Huang, He,Li, Huiying,Yang, Sun,Chreifi, Georges,Martásek, Pavel,Roman, Linda J.,Meyskens, Frank L.,Poulos, Thomas L.,Silverman, Richard B.
, p. 686 - 700 (2014/03/21)
Selective inhibitors of neuronal nitric oxide synthase (nNOS) are regarded as valuable and powerful agents with therapeutic potential for the treatment of chronic neurodegenerative pathologies and human melanoma. Here, we describe a novel hybrid strategy
Thiophene-2-carboximidamide Based Selective Neuronal Nitric Oxide Inhibitors
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Paragraph 0030, (2014/03/25)
Selective neuronal nitric oxide synthase (nNOS) inhibitor compounds designed with one or more thiophene-2-carboximidamide substituents for improved bioavailability.
Guanidine compound and heat sensitive recording material
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Page column 35, (2010/01/30)
An object of the present invention is to provide a heat sensitive recording material which can develop color at high density by the inclusion of a novel guanidine compound which is strongly basic and superior in diffusion resistance. The present invention for attaining the above-described object is a heat sensitive recording material comprising a substrate supporting thereon a heat sensitive recording layer containing a diazonium salt compound, a coupler which reacts with the diazonium salt compound when heated to develop color, and abase, wherein the heat sensitive recording layer includes as the base at least one of the guanidine compounds represented by the general formula (1): wherein, in the general formula (1), R1and R2represent an alkyl group or aryl group and may be the same or different, R3and R4represent a hydrogen atom, alkyl group or halogen atom and may be the same or different, and X represents a divalent connecting group.
