144699-08-1

Upstream product

• 144699-11-6 (3S,5S)-3,5-bis(tert-butyldimethylsilyloxy)cyclohex-1-enecarbaldehyde 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 144699-09-2 (3S,4S,5S)-3,5-bis(tert-butyldimethylsilyloxy)-1-hydroxymethyl-4-phenoxythiocarbonyloxycyclohex-1-ene 
• 101906-40-5 methyl (3S,4S,5S)-3,5-bis(tert-butyldimethylsilyloxy)-4-phenoxythiocarbonyloxycyclohex-1-enecarboxylate 
• 101906-39-2 Methyl (3R,4R,5R)-3,5-Bis<(tert-butyl)dimethylsilyloxy>-4-hydroxycyclohex-1-ene-1-carboxylate 
• 40983-58-2 methyl shikimate 
• 138-59-0 shikimic acid 
• 262594-22-9 methyl (3S,5R)-3,5-di[(tert-butyldimethylsilyl)oxy]-cyclohex-1-enecarboxylate 
• 144699-10-5 (3S,5S)-3,5-bis(tert-butyldimethylsilyloxy)-1-hydroxymethylcyclohex-1-ene 
• 139356-33-5 (3S,5S)-3,5-bis[(tert-butyl)dimethylsilyloxy]-1-hydroxycyclohexane-1-carboxylic acid methyl ester 
• 77-95-2 D-(-)-quinic acid 

Downstream Products

• 262594-19-4 (1R,3S)-5-[(1R,3aR,7aR)-1-((1R)-5-hydroxy-1,5-dimethylhexyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]ethynylcyclohex-4-ene-1,3-diol 
• 350985-74-9 (3S,5R)-1-ethynyl-3,5-dihydroxycyclohex-1-ene 
• 530147-41-2 (3R,3aR,7aR)-7-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-1-enylethynyl]-3-((R)-1,5-dimethyl-5-triethylsilanyloxy-hexyl)-3a-methyl-2,3,3a,4,5,7a-hexahydro-1H-indene 
• 530147-43-4 (4R,4aR,8aR)-8-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-1-enylethynyl]-4-((R)-1,5-dimethyl-5-triethylsilanyloxy-hexyl)-4a-methyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalene 
• 144699-06-9 (1R,3S)-5-[(Z)-2-[(1R,3aR,7aR)-1-((1R)-5-hydroxy-1,5-dimethylhexyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]ethenyl]cyclohex-4-ene-1,3-diol 
• 1180846-41-6 C₅₀H₈₆O₄Si₄ 
• 144717-32-8 (R)-6-{(1R,3aR,7aR)-4-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-1-enylethynyl]-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-1-yl}-2-methyl-heptan-2-ol 
• 1298075-90-7 14-epi-1α,25-dihydroxy-19-nortachysterol 

Relevant academic research and scientific papers

Synthesis of two 6-s-cis locked stereoisomeric analogues of the steroid hormone 1α,25-dihydroxyvitamin D3: 1 α,25-dihydroxy-19-nor-previtamin D3 and 1β,25-dihydroxy- 19-nor-previtamin D3

An efficient synthesis of A-ring precursors 8 and 9 from inexpensive commercially available (-)-quinic acid has been developed. A-Ring synthon 8 has been obtained through a short sequence (eight steps) in high overall yield (30%). One key step in the synt

Synthesis of 1α,25-Dihydroxy-19-norprevitamin D3

We describe a convergent synthesis of 1α,25-dihydroxy-19-norprevitamin D3 (3), an analogue of the hormone 1α,25-dihydroxyvitamin D3 (1c), that is locked into the previtamin form.