1447285-55-3Relevant academic research and scientific papers
Sodium hydride-mediated synthesis of 1,5-diaryl-1,2,3-triazoles from anti-3-aryl-2,3-dibromopropanoic acids and organic azides
Cheng, Xue-Zhi,Liu, Wei,Huang, Zhen-Dong,Kuang, Chun-Xiang
, p. 764 - 766 (2013)
A series of 1,5-disubstituted 1,2,3-triazoles are synthesized by a one-pot process from anti-3-aryl-2,3-dibromopropanoic acids and organic azides mediated by sodium hydride in dimethyl sulfoxide. The reaction is mild and simple, does not require a transition-metal catalyst, and gives products in good to excellent yields.
