3302-39-4

Basic information

• Product Name: 1-Azido-2-bromobenzene
• Synonyms: 1-Azido-2-bromobenzene;1-Azido-2-broMobenzene solution;2-Bromophenyl azide solution
• CAS NO: 3302-39-4
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 0
• Mol File: 3302-39-4.mol
• Article Data: 44

Chemical Properties

• Flash Point: -33℃
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: 1-Azido-2-bromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azido-2-bromobenzene(3302-39-4)
• EPA Substance Registry System: 1-Azido-2-bromobenzene(3302-39-4)

Safety Data

• Hazard Codes: F,T
• Statements: 11-38-39/23/24/25
• Safety Statements: 16
• RIDADR: UN 2398 3 / PGII
• Hazardous Substances Data: 3302-39-4(Hazardous Substances Data)

Usage

Functional groups

Azide and bromine

Structure

Combination of benzene with azide and bromine groups

Applications

a. Organic synthesis
b. Pharmaceutical production
c. Dye production
d. Chemical production
e. Precursor to various intermediates

Hazardous nature

Toxic and explosive

Safety precautions

Must be handled with care

Upstream product

• 10448-07-4 2-bromobenzenediazonium tetrafluoroborate 
• 577-19-5 2-nitrophenyl bromide 
• 244205-40-1 (2-bromophenyl)boronic acid 
• 615-36-1 2-bromoaniline 
• 34835-57-9 2-bromo benzene diazonium chloride 
• 19519-75-6 1-bromo-2-nitrosobenzene 

Downstream Products

• 615-36-1 2-bromoaniline 
• 925699-40-7 C₁₅H₁₄BrNO 
• 159528-54-8 2,2'-bis(triphenylphosphoranylidenamino)diphenylamine 
• 1039325-60-4 C₉H₆BrN₃O₂ 

Relevant articles and documents

N2 Activation by an Iron Complex with a Strong Electron-Donating Iminophosphorane Ligand

A new tridentate cyclopentane-bridged iminophosphorane ligand, N-(2-diisopropylphosphinophenyl)-P,P-diisopropyl-P-(2-(2,6-diisopropylphenylamido)cyclopent-1-enyl)phosphoranimine (NpNPiPr), was synthesized and used in the preparation of a diiron

Synthesis, antimicrobial evaluation, and in silico studies of quinoline—1H-1,2,3-triazole molecular hybrids

Abstract: Antimicrobial resistance has become a significant threat to global public health, thus precipitating an exigent need for new drugs with improved therapeutic efficacy. In this regard, molecular hybridization is deemed as a viable strategy to afford multi-target-based drug candidates. Herein, we report a library of quinoline—1H-1,2,3-triazole molecular hybrids synthesized via copper(I)-catalyzed azide-alkyne [3 + 2] dipolar cycloaddition reaction (CuAAC). Antimicrobial evaluation identified compound 16 as the most active hybrid in the library with a broad-spectrum antibacterial activity at an MIC80 value of 75.39?μM against methicillin-resistant S. aureus, E. coli, A. baumannii, and multidrug-resistant K. pneumoniae. The compound also showed interesting antifungal profile against C. albicans and C. neoformans at an MIC80 value of 37.69 and 2.36?μM, respectively, superior to fluconazole. In vitro toxicity profiling revealed non-hemolytic activity against human red blood cells (hRBC) but partial cytotoxicity to human embryonic kidney cells (HEK293). Additionally, in silico studies predicted excellent drug-like properties and the importance of triazole ring in stabilizing the complexation with target proteins. Overall, these results present compound 16 as a promising scaffold on which other molecules can be modeled to deliver new antimicrobial agents with improved potency. Graphic abstract: [Figure not available: see fulltext.].

New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives

In the present work, we report a new class of potent steroid sulphatase (STS) inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives. Within the set of new STS inhibitors, 6-(1-(1,2,3-trifluorophenyl)-1H-1,2,3-triazol