1447343-90-9Relevant articles and documents
Various cyclization scaffolds by a truly Ugi 4-CR
Sinha, Mantosh K.,Khoury, Kareem,Herdtweck, Eberhardt,D?mling, Alexander
supporting information, p. 4792 - 4796 (2013/07/26)
Efficient access to a large chemical space based on new scaffolds with defined 3D conformations and highly variable in the side chains is needed to find novel functional materials. Four heterocyclic scaffolds based on a four component Ugi reaction of α-amino acids, oxo components, isocyanides and primary or secondary amines suitably functionalized are described. A handful of examples are described for each scaffold.