14474-71-6 Usage
Uses
Used in Pharmaceutical Industry:
2,5-Piperazinedione, 3-benzyl-6-isopropylis utilized as a pharmaceutical intermediate for the synthesis of various drugs. Its structural properties allow it to serve as a building block in the creation of new medicinal compounds, contributing to the development of novel treatments for an array of medical conditions.
Used in Medicinal Chemistry Research:
2,5-Piperazinedione, 3-benzyl-6-isopropylis also employed in the field of medicinal chemistry for research and development purposes. Its biological activities and potential applications in drug discovery make it an intriguing subject for scientists seeking to innovate and enhance pharmaceutical offerings.
Check Digit Verification of cas no
The CAS Registry Mumber 14474-71-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,4,7 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 14474-71:
(7*1)+(6*4)+(5*4)+(4*7)+(3*4)+(2*7)+(1*1)=106
106 % 10 = 6
So 14474-71-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2O2/c1-9(2)12-14(18)15-11(13(17)16-12)8-10-6-4-3-5-7-10/h3-7,9,11-12H,8H2,1-2H3,(H,15,18)(H,16,17)
14474-71-6Relevant academic research and scientific papers
Conformational effects in reversed-phase liquid chromatographic separation of diastereomers of cyclic dipeptides
Funasaki, Noriaki,Hada, Sakae,Neya, Saburo
, p. 1861 - 1867 (2007/10/02)
The capacity factors, k′, of 11 cyclic dipeptides (X-Y) including diastereomers have been determined on an RP-HPLC column in 30% and 50% methanol and 10%, 30%, and 50% acetonitrile solutions. These factors are roughly correlated with hydrophobic parameters, such as octanol-water partition coefficients estimated and k′ values for alcohols. For a pair of diastereomers of cyclic (L-X-L-Phe) and (L-X-D-Phe) derivatives k′LL is larger than k′LD and for cyclic (D-Ala-L-Trp) and (L-Ala-L-Trp) k′LL is smaller than k′DL, particularly in highly aqueous solutions. These elution orders can be well predicted by the holistic molecular surface area approach which takes into account the folded structures of cyclic dipeptides. The present results will be useful for prediction of the log k′ values of larger peptides and the hydrophobicity and related properties of peptides.
