144754-25-6

Basic information

• Product Name: (2S,3R) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanoate
• Synonyms: (2S,3R) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanoate
• CAS NO: 144754-25-6
• Molecular Weight: 606.716
• Mol File: 144754-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanoate(144754-25-6)
• EPA Substance Registry System: (2S,3R) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanoate(144754-25-6)

Safety Data

• Hazardous Substances Data: 144754-25-6(Hazardous Substances Data)

Upstream product

• 870-50-8 di-tert-butyl-diazodicarboxylate 
• 144754-24-5 methyl (R)-3-hydroxy-4-(triphenylmethyl)oxybutanoate 
• 76-83-5 trityl chloride 
• 114819-45-3 (R)-methyl 3,4-dihydroxybutanoate 

Downstream Products

• 144754-28-9 (3S,4S) 1-(benzyloxy)-3--4-hydroxymethyl-2-azetidinone 
• 144754-26-7 (2S,3R) benzyl 2--3-hydroxy-4-(triphenylmethoxy)-butanohydroxamate 
• 159801-14-6 (3S,4S) 3--1-(methoxy)-4-<(triphenylmethoxy)methyl>-2-azetidinone 
• 159801-13-5 (2S,3S) methyl 2--3-hydroxy-4-(triphenylmethoxy)-butanohydroxamate 

Relevant articles and documents

Enantiospecific and Diastereoselective Synthesis of cis Monobactams through Electrophilic Amination of Chiral 3-Hydroxyesters

A new efficient entry into cis monobactams starting from β-hydroxyesters is reported.This preparation is based on the stereoselective "electrophilic amination" of β-hydroxyester dianions and on Miller's biomimetic synthesis of the β-lactam nucleus.By this route, key intermediates for the preparation of pharmacologically important cis aztreonam 2 and carumonam 3 were prepared.