144760-46-3

Basic information

• Product Name: chloromethyl-dimethyl-(p-methoxycinnamyl)silane
• Synonyms: chloromethyl-dimethyl-(p-methoxycinnamyl)silane
• CAS NO: 144760-46-3
• Molecular Weight: 254.832
• Mol File: 144760-46-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: chloromethyl-dimethyl-(p-methoxycinnamyl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: chloromethyl-dimethyl-(p-methoxycinnamyl)silane(144760-46-3)
• EPA Substance Registry System: chloromethyl-dimethyl-(p-methoxycinnamyl)silane(144760-46-3)

Safety Data

• Hazardous Substances Data: 144760-46-3(Hazardous Substances Data)

Upstream product

• 140-67-0 Estragole 
• 1719-57-9 Chloro(chloromethyl)dimethylsilane 

Downstream Products

• 144760-47-4 (S)-1-({[(E)-(S)-1-Ethyl-3-(4-methoxy-phenyl)-allyl]-dimethyl-silanyl}-methyl)-2-methoxymethyl-pyrrolidine 
• 144760-47-4 (S)-1-({[(E)-(R)-1-Ethyl-3-(4-methoxy-phenyl)-allyl]-dimethyl-silanyl}-methyl)-2-methoxymethyl-pyrrolidine 
• 144760-32-7 (S)-2-Methoxymethyl-1-({[(E)-(S)-3-(4-methoxy-phenyl)-1-methyl-allyl]-dimethyl-silanyl}-methyl)-pyrrolidine 
• 144760-44-1 (S)-2-Methoxymethyl-1-({[(E)-(R)-3-(4-methoxy-phenyl)-1-methyl-allyl]-dimethyl-silanyl}-methyl)-pyrrolidine 
• 144760-40-7 (S)-2-Methoxymethyl-1-({[(E)-3-(4-methoxy-phenyl)-pent-1-enyl]-dimethyl-silanyl}-methyl)-pyrrolidine 
• 144760-33-8 (S)-2-Methoxymethyl-1-({[(E)-3-(4-methoxy-phenyl)-but-1-enyl]-dimethyl-silanyl}-methyl)-pyrrolidine 
• 144760-31-6 dimethyl-(p-methoxycinnamyl)-<(S)-2'-methoxymethylpyrrolidinylmethyl>silane 

Relevant articles and documents

Chiral organosilicon compounds in synthesis. Preparation and stereoselective alkylations of silylcinnamyl carbanions

Silylallyl carbanions of type 13 bearing a chiral lithium complexing substituent remote from silicon can be alkylated regio- and stereoselectively at the α-position by small electrophiles in nonpolar solvents.The regiochemical outcome of the reaction was found to be highly dependent on the size of the incoming electrophile.Secondary alkyl halides react preferentially at the γ-center and good levels of stereoselectivity are still obtained in nonpolar solvents despite the rather long distance between the reacting center and the chiral auxiliary.Transformation of the alkylated allylsilanes into optically active alcohols and carboxylic acids may represent a potential synthetic application of the method.