144760-53-2Relevant academic research and scientific papers
Phthalimidosulfenyl chloride. Part 5. Reaction with enolizable carbonyl compounds and synthesis of functionalized thiones
Capozzi, Giuseppe,Menichetti, Stefano,Nativi, Cristina,Rosi, Alessandro,Valle, Giovanni
, p. 9023 - 9032 (1992)
β-Ketothio derivatives 4, prepared by reaction of phthalimidosulphenyl chloride with enolizable carbonyl compounds, afford, in presence of pyridine, unstable functionalized thiones which can be trapped with 1,3-dienes to give the corresponding cycloadditi
α-Oxosulfines: New Generation Methods and Reactivity
Capozzi, Giuseppe,Corti, Alessandra,Menichetti, Stefano,Nativi, Cristina
, p. 317 - 318 (2007/10/03)
α-oxothiophthalimides 2 can be oxidised the corresponding sulfinimides 3 with m-chloroperoxybenzoic acid.Derivatives 3 in the presence of catalytic amount of pyridine generate the α-oxosulfines 4 which can be trapped by diene 5 to give dihydrothiopyranes 6 as mixture of diastereoisomers.The method appears simple and general since alkyl, aryl and hetroaryl substituted thiophthalimides can be fruitfully used.
