1447648-36-3

Upstream product

• 288-88-0 1,2,4-Triazole 
• 25596-24-1 trimethyloxosulfonium bromide 
• 1311402-88-6 1-(4-chlorobenzyl)-3,3-bis(hydroxymethyl)-2-oxocyclopentane carboxylic acid methyl ester 
• 41253-21-8 sodium triazole 
• 115851-73-5 1-[(4-chlorophenyl)methyl]-2-oxocyclopentanecarboxylic acid methyl ester 
• 865-48-5 sodium t-butanolate 

Relevant academic research and scientific papers

METHOD FOR PRODUCING AZOLE DERIVATIVE

In the present invention, a compound (I) is reacted with a base selected from the group consisting of a metal alkoxide, a metal hydride compound, an alkali metal, an organometallic compound of an alkali metal, an alkali metal amide, an alkali metal carbonate salt, an alkali earth metal carbonate salt, and a mixture of these to produce a compound (II). Thereafter, this reaction solution is mixed with a compound (III) and a sulfonium compound or a sulfoxonium compound in the presence of a base to obtain an azole derivative (V).

METHOD FOR PRODUCING CYCLOPENTANOL DERIVATIVE

PROBLEM TO BE SOLVED: To provide a method for producing a cyclopentanol derivative (I) at low cost and with high yield. SOLUTION: There is provided a method for producing a cyclopentanol derivative (I) which comprises a reaction step of azolylmethylating

METHOD FOR PRODUCING CYCLOPENTANONE DERIVATIVE, INTERMEDIATE COMPOUND, AND METHOD FOR PRODUCING INTERMEDIATE COMPOUND

A method for producing a cyclopentanone derivative represented by general formula (III) below, wherein a cyclopentanone derivative represented by general formula (III) below can be produced with higher yield since the method comprises a step in which a compound represented by general formula (II) below is obtained by reacting a compound represented by general formula (I) below with an acid.

METHOD FOR PRODUCING CYCLOALKANOL DERIVATIVE, AND METHOD FOR PRODUCING AZOLE DERIVATIVE

Provided are: a method for producing a cycloalkanol derivative that enables the production of an azole derivative at low cost and with high yield; and a method for producing an azole derivative. In a process of producing a cycloalkanol derivative represented by general formula (I), a reaction step of azolylmethylating a cycloalkanone derivative represented by general formula (II) is carried out using an azole compound represented by general formula (III) in the presence of a sulfur ylide. In this step, the sulfur ylide is produced from a sulfonium compound or sulfoxonium compound and an alkali metal methoxide in a reaction system.

AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND

In order to provide a novel azole derivative, an azole derivative of the present invention is an azole derivative represented by a general formula (V'). (where R6 and R7 independently represent a hydrogen atom, a C1-C4 alkyl group, a phenyl group, or a benzyl group; X represents a halogen atom, a C1-C4 alkyl group, a haloalkyl group, an alkoxy group or a haloalkoxy group, a phenyl group, a cyano group, or a nitro group; m represents an integer of 0 to 5; and A represents a nitrogen atom or a methyne group.)