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2-(3,5-bis-(4-fluoro-phenyl)-(1,2,4)triazol-1-yl)-1-(4-(6-dimethylamino-pyrimidin-4-yl)-piperazin-1-yl)-ethanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1447726-01-3

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1447726-01-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1447726-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,7,7,2 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1447726-01:
(9*1)+(8*4)+(7*4)+(6*7)+(5*7)+(4*2)+(3*6)+(2*0)+(1*1)=173
173 % 10 = 3
So 1447726-01-3 is a valid CAS Registry Number.

1447726-01-3Downstream Products

1447726-01-3Relevant academic research and scientific papers

SUBSTITUTED TRIAZOLES AND THEIR USE FOR TREATMENT AND/OR PREVENTION NEUROLOGICAL AND PSYCHIATRIC DISORDERS

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Page/Page column 137, (2013/07/31)

This invention relates to compounds of formula (I), their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.

NOVEL COMPOUNDS

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Paragraph 0390; 0391, (2013/07/25)

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.

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