1447759-51-4Relevant articles and documents
Catalyst-free Synthesis of pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivatives by Aza-Diels-Alder reaction
Quiroga, Jairo,Valencia, Angela,Perez, Alfredo,Galvez, Jaime,Abonia, Rodrigo,Insuasty, Braulio
, p. 337 - 341 (2013/07/26)
A series of pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivatives was synthesized via catalyst-free bi-component and one-pot reactions of 5-Aminopyrazoles, DMF-DMA (or TMOF) and N-Arylmaleimides in xylene as solvent. This protocol showed advantages of milder reaction conditions, easier work-up, shorter reaction times and good yields, over other approaches tested.