144776-75-0Relevant academic research and scientific papers
Regioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds
McLaughlin, Mark G.,Roberts, Dean D.
supporting information, p. 4463 - 4467 (2021/06/28)
We describe, for the first time, a highly regioselective hydrosilylation of propargylic amines. The reaction utilizes a PtCl2/XantPhos catalyst system to deliver hydrosilanes across the alkyne to afford multifunctional allylic amines in high yields. The reaction is tolerant to a wide variety of functional groups and provides high value intermediates with two distinct functional handles. The synthetic applicability of the reaction has been shown through the synthesis of diverse ambiphilic aziridines.
Synthesis of 5-vinylideneoxazolidin-2-ones by DBU-mediated CO 2-fixation reaction of 4-(benzylamino)-2-butynyl carbonates and benzoates
Yoshida, Masahiro,Komatsuzaki, Yuki,Ihara, Masataka
supporting information; experimental part, p. 2083 - 2086 (2009/04/18)
A CO2-fixation reaction of 4-(benzylamino)-2-butynyl carbonates and benzoates, carried out in the presence of DBU, provides substituted 5-vinylideneoxazolidin-2-ones. The reaction has been successfully applied to the CO2-recycling process and fixation of atmospheric CO2.
An unprecedented Pd-catalyzed, water-promoted sequential oxidative aminocarbonylation-cyclocarbonylation process leading to 2-oxazolidinones
Gabriele, Bartolo,Plastina, Pierluigi,Salerno, Giuseppe,Mancuso, Raffaella,Costa, Mirco
, p. 3319 - 3322 (2008/02/12)
An unprecedented, Pdl2-catalyzed, sequential oxidative aminocarbonylation-cyclocarbonylation process, leading to 2-oxazolidinone derivatives 3 in good to excellent yields starting from readily available α,α-disubstituted 2-ynylamines 1 and secondary amines 2, is reported. In the case of an α-monosubstituted substrate, the initially formed 2-oxazolidinone derivative underwent shift of the double bond to give a 3H-oxazol-2-one derivative in excellent isolated yield.
