14478-92-3Relevant academic research and scientific papers
REACTION OF α-HALOHYDRAZONES WITH PRIMARY THIOAMIDES
Benincori, Tiziana,Brenna, Elisabetta,Sannicolo, Franco,Trimarco, Licia,Pilati, Tullio
, p. 531 - 538 (2007/10/02)
The reaction of several α-chloroarylhydrazones, 2, with thioacetamide or a thioacetamide-thiobenzamide mixture in refluxing toluene affords 5-substituted-2,3-dihydro-3-aryl-2-(thioacyl)methylene-1,3,4-thiadiazoles, 5.Two 1,6-dithia-3,4-diazaspironona-2,8-diene derivatives (6) and a 1,3,4-thiadiazepine derivative (7) obtained as by-products are the first examples of these heterocyclic systems.
Acylation of N'-Arylbenzothiohydrazides and of their N'-Acyl-derivatives; 2-Acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes and Related Compounds
Callaghan, Patrick D.,Elliott, Arthur J.,Gandhi, Sham S.,Gibson, Martin S.,Mastalerz, Harold,Vukov, Darko J.
, p. 2948 - 2951 (2007/10/02)
Reactions of N'-arylbenzothiohydrazides and of their N-acyl-derivatives with carboxylic anhydrides under various sets of conditions are shown to lead to 2-acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes.The probable mechanism of formation of these compounds via the corresponding 2-alkylidenethiadiazolene as intermediate is discussed.
