144783-46-0 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(4-Morpholino-3-nitrophenyl)-1-ethanone is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 1-(4-Morpholino-3-nitrophenyl)-1-ethanone is utilized as a precursor in the creation of agrochemicals, potentially enhancing crop protection and yield.
Used in Material Science:
1-(4-Morpholino-3-nitrophenyl)-1-ethanone is employed as a component in the development of functional materials, leveraging its structural and reactive characteristics to produce materials with specific properties for various applications.
Used in Dye and Organic Compound Production:
MNE serves as a precursor in the production of certain dyes and organic compounds, contributing to the coloration and functional attributes of these products.
Check Digit Verification of cas no
The CAS Registry Mumber 144783-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,7,8 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 144783-46:
(8*1)+(7*4)+(6*4)+(5*7)+(4*8)+(3*3)+(2*4)+(1*6)=150
150 % 10 = 0
So 144783-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O4/c1-9(15)10-2-3-11(12(8-10)14(16)17)13-4-6-18-7-5-13/h2-3,8H,4-7H2,1H3
144783-46-0Relevant academic research and scientific papers
Hu, Hao,Li, Ming,Wu, Di,Li, Zhiwei,Miao, Ruifeng,Liu, Yajing,Gong, Ping
, p. 3135 - 3144 (2019)
Two series of novel aryl-acrylic derivatives were designed, synthesized, and screened in enzymatic and cellular inhibitory activities. All compounds showed moderate to significant potency. The SAR analyses indicated that the semicarbazone linker is better
HETEROCYCLES USEFUL AS IDO AND TDO INHIBITORS
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Paragraph 125, (2016/10/31)
Provided are compounds of Formula (I) shown below using for treatment of diseases or disorders mediated by IDO and/or TDO, pharmaceutical compositions and methods of preparation thereof.
Synthesis of &β-amino substituted 4-amino-3-nitropropiophenones as diethylcarbamazine analogs and their antifilarial activity
Varma, Rajendra S,Sarin, Simi,Chatterjee, R K
, p. 711 - 713 (2007/10/02)
A number of β-amino substituted 4-amino-3-nitropropiophenones (5-16) have been synthesised and evaluated against filariasis.Compounds 14,10 and 13 show 77.5percent, 74.4percent and 82.2percent microfilaricidal activity respectively, at 30 mg/kg for 5 days by i.p. route.Compound 14 also show 60.3percent adulticidal activity.
