400-93-1

Basic information

• Product Name: 4'-Fluoro-3'-nitroacetophenone
• Synonyms: 4'-Fluoro-3'-nitroacetophenone,98%;1-(4-Fluoro-3-nitrophenyl)ethan-1-one;1-(4-Fluoro-3-nitrophenyl)ethan-1-one, 5-Acetyl-2-fluoronitrobenzene;4-Fluoro-3-nitroacetophneone;4′-Fluor-3′-nitroacetophenon;4'-Fluoro-3'-notroacetophenone;Ethanone, 1-(4-fluoro-3-nitrophenyl)-;1-(4-FLUORO-3-NITRO-PHENYL)-ETHANONE
• CAS NO: 400-93-1
• Molecular Formula: C₈H₆FNO₃
• Molecular Weight: 183.14
• EINECS: -0
• Product Categories: Carbonyl Compounds;Ketones;Acetophenone series;ketone;Miscellaneous;C7 to C8
• Mol File: 400-93-1.mol
• Article Data: 14

Chemical Properties

• Melting Point: 46-50 °C
• Boiling Point: 118-120°C 0,8mm
• Flash Point: 118-120°C/0.8mm
• Appearance: Light yellow/Crystalline Powder
• Density: 1.336 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• BRN: 2211976
• CAS DataBase Reference: 4'-Fluoro-3'-nitroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Fluoro-3'-nitroacetophenone(400-93-1)
• EPA Substance Registry System: 4'-Fluoro-3'-nitroacetophenone(400-93-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 400-93-1(Hazardous Substances Data)

Usage

Chemical Properties

light yellow crystalline powder

Uses

4''-?Fluoro-?3''-?nitroacetophenone is used as reactant/reagent in preparation of substituted furans via copper-catalyzed radical addition of acetophenones to alkynes.

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 

Downstream Products

• 54375-49-4 1-(3-nitro-4-propoxyphenyl)ethan-1-one 
• 31438-66-1 Resorcin-bis-<2-nitro-4-acetyl-phenyl>-aether 
• 1432-42-4 1-(4-amino-3-nitrophenyl)ethanone 

Relevant articles and documents

Profiling the interaction of a novel toxic pyruvate dehydrogenase kinase inhibitor with human serum albumin

To discover novel pyruvate dehydrogenase kinase (PDK) inhibitors, a new compound 2,2-dichloro-1-(4-((4-isopropylphenyl)amino)-3-nitrophenyl)ethan-1-one, namely XB-1 was identified, which inhibited PDK activity with a half maximal inhibitory concentration

Semicarbazone compounds and application thereof

The invention belongs to the technical field of medicines, and relates to semicarbazone compounds as shown in a general formula I and pharmaceutically acceptable salts, hydrates or prodrugs thereof, wherein the definitions of substituent groups R1, R2, R3

Thiazole derivative compounds having IDO inhibitory activity, preparation method and application thereof

The invention relates to the technical field of medicinal chemistry, in particular to thiazole derivative compounds having IDO (indoleamine-2,3-dioxygenase) inhibitory activity, a preparation method and application thereof. The invention discloses thiazol