1447840-64-3Relevant academic research and scientific papers
A convergent and stereoselective total synthesis of (-)-crispine A, (-)-benzo[a]quinolizidine and (-)-salsolidine
Reddy, N. Siva Senkar,Reddy, B. Jagan Mohan,Reddy, B.V. Subba
, p. 4228 - 4231 (2013)
A novel strategy has been developed for the syntheses of (-)-crispine, (-)-benzo[a]quinolizidine, and (-)-salsolidine using (R)-tert-butanesulfinamide as a source of chirality. The approach involves the stereoselective addition of Grignard reagent to chiral N-sulfinyl imine followed by cyclization of the secondary amide with a tethered halide as key steps.
