1448013-36-2

Upstream product

• 1448013-34-0 2-N-acetyl-6-O-allyl-3,4-di-O-benzyl-α-D-glucosaminopyranosyl-(1→3)-2-N-acetyl-4-O-benzyl-6-O-levulinoyl-α-D-glucosaminopyranosyl-(1→2)-benzyl (2R)-3-benzyloxypropanoate 
• 1448013-23-7 2-N-acetyl-3,4-di-O-benzyl-6-O-prop-1-en-α-D-glucosaminopyranosyl-(1→3)-2-N-acetyl-4-O-benzyl-α-D-glucosaminopyranosyl-(1→2)-benzyl (2R)-3-benzyloxypropanoate 
• 10433-52-0 O-benzyl-D-serine 
• 127744-27-8 3-(benzyloxy)-(R)-2-hydroxy-propionic acid 
• 138923-10-1 2-azido-4,6-O-benzylidene-2-deoxyl-1-O-tert-butyldimethylsilyl-β-D-glucopyranoside 
• 1448013-28-2 2-azido-4,6-O-benzylidene-1-O-tert-butyldimethylsilyl-2-deoxy-3-O-(2-naphthalenylmethyl)-D-glucopyranoside 
• 444118-38-1 tert-butyldimethylsilyl 6-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 1448013-26-0 2-azido-4-O-benzyl-2-deoxy-6-O-levulinoyl-3-O-(2-naphthalenylmethyl)-D-glucopyranosyl trichloroacetimidate 
• 1448013-27-1 6-O-allyl-2-azido-3,4-di-O-benzyl-2-deoxy-D-glucopyranosyl trichloroacetimidate 
• 1448013-31-7 2-azido-4-O-benzyl-2-deoxy-6-O-levulinoyl-3-O-(2-naphthalenylmethyl)-α-D-glucopyranosyl-(1→2)-benzyl (2R)-3-benzyloxypropanoate 
• 1448013-32-8 2-azido-4-O-benzyl-2-deoxy-6-O-levulinoyl-α-D-glucopyranosyl-(1→2)-benzyl (2R)-3-benzyloxypropanoate 
• 1448013-33-9 6-O-allyl-2-azido-3,4-di-O-benzyl-2-deoxy-α-D-glucopyranosyl-(1→3)-2-azido-4-O-benzyl-2-deoxy-6-O-levulinoyl-α-D-glucopyranosyl-(1→2)-benzyl (2R)-3-benzyloxypropanoate 

Relevant academic research and scientific papers

Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine

Clostridium difficile is a leading cause of severe nosocomial infections. Cell-surface carbohydrate antigens are promising vaccine candidates. Here we report the first total synthesis of oligomers of the lipoteichoic acid antigen repeating unit. Synthetic glycan microarrays revealed anti-glycan antibodies in the blood of patients that help to define epitopes for vaccine development.