1448013-28-2Relevant academic research and scientific papers
One-Pot Protection Strategy of Glucosamine to Assemble Building Blocks of Chitosan and Lipid A
Chen, Jyun-Siao,Huang, Po-Hsun,Lin, Yi-Jyun,Liu, Jen-Wei,Liu, Yu-Hao,Luo, Shun-Yuan,Pantawane, Amit Ravindra,Sankar, Arumugam,Wu, Hsin-Ru
, (2020/08/21)
This investigation describes a one-pot reaction to prepare a series of building blocks for glycosylation reactions, such as 3-alcohol glucosamines, fully protected glucosamines, O-4 and O-6 alcohol glucosamines. These reactions readily produce not only gl
Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine
Martin, Christopher E.,Broecker, Felix,Eller, Steffen,Oberli, Matthias A.,Anish, Chakkumkal,Pereira, Claney L.,Seeberger, Peter H.
supporting information, p. 7159 - 7161 (2013/08/23)
Clostridium difficile is a leading cause of severe nosocomial infections. Cell-surface carbohydrate antigens are promising vaccine candidates. Here we report the first total synthesis of oligomers of the lipoteichoic acid antigen repeating unit. Synthetic glycan microarrays revealed anti-glycan antibodies in the blood of patients that help to define epitopes for vaccine development.
