1448153-99-8

Basic information

• Product Name: 1-phenethyl-2-phenyl-1H-pyrrole
• Synonyms: 1-phenethyl-2-phenyl-1H-pyrrole
• CAS NO: 1448153-99-8
• Molecular Weight: 247.34
• Mol File: 1448153-99-8.mol

Chemical Properties

• CAS DataBase Reference: 1-phenethyl-2-phenyl-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenethyl-2-phenyl-1H-pyrrole(1448153-99-8)
• EPA Substance Registry System: 1-phenethyl-2-phenyl-1H-pyrrole(1448153-99-8)

Safety Data

• Hazardous Substances Data: 1448153-99-8(Hazardous Substances Data)

Upstream product

• 107-21-1 ethylene glycol 
• 64-04-0 phenethylamine 
• 98-86-2 acetophenone 

Relevant articles and documents

Efficient [Cu(NHC)]-Catalyzed Multicomponent Synthesis of Pyrroles

Efficient [Cu(NHC)]-catalyzed syntheses of pyrroles via two and three-component coupling methods are described. Various 1,2-, 1,2,3-, 1,2,3,5- and fully substituted pyrroles were readily accessible through a suitable choice of ketone, primary amine and diol in a three-component reaction. The N-unsubstituted pyrrole formation is also feasible through a two-component reaction involving a β-amino alcohol and a ketone.

Multicomponent reactions in PEG-400: Ruthenium-catalyzed synthesis of substituted pyrroles

An efficient and eco-friendly method for the synthesis of substituted pyrroles has been developed via ruthenium-catalyzed multicomponent reaction of ketone, amine, and ethylene glycol in PEG-400 as solvent medium without using any external ligand. The cat

Manganese-Catalyzed Multicomponent Synthesis of Pyrroles through Acceptorless Dehydrogenation Hydrogen Autotransfer Catalysis: Experiment and Computation

A new base metal catalyzed sustainable multicomponent synthesis of pyrroles from readily available substrates is reported. The developed protocol utilizes an air- and moisture-stable catalyst system and enables the replacement of themutagenic α-haloketones with readily abundant 1,2-diols. Moreover, the presented method is catalytic in base and the sole byproducts of this transformation are water and hydrogen gas. Experimental and computational mechanistic studies indicate that the reaction takes place through a combined acceptorless dehydrogenation hydrogen autotransfer methodology.

General and regioselective synthesis of pyrroles via ruthenium-catalyzed multicomponent reactions

A general and highly regioselective synthesis of pyrroles via ruthenium-catalyzed three-component reactions has been developed. A variety of ketones including less reactive aryl and alkyl substrates were efficiently converted in combination with different