1448195-75-2Relevant academic research and scientific papers
Stereoselective Alkyne Hydrohalogenation by Trapping of Transfer Hydrogenation Intermediates
Das, Manas,Kaicharla, Trinadh,Teichert, Johannes F.
, p. 4926 - 4929 (2018)
A catalytically generated vinylcopper complex, the reactive intermediate of a copper(I)-catalyzed alkyne transfer hydrogenation, can be trapped by commercially available halogen electrophiles. In this manner, internal alkynes can stereoselectively be hydrohalogenated to the corresponding vinyl chlorides, bromides, and iodides.
