287481-54-3Relevant academic research and scientific papers
Bis(2,2,2-trifluoroethyl)bromophosphono-acetate, a novel HWE reagent for the preparation of (E)-α-bromoacrylates: A general and stereoselective method for the synthesis of trisubstituted alkenes
Tago, Keiko,Kogen, Hiroshi
, p. 1975 - 1978 (2000)
(Equation presented) A novel reagent, methyl bis(2,2,2-trifluoroethoxy)bromophosphonoacetate (3a), was designed and prepared in order to efficiently synthesize (E)-α-bromoacrylates, which are useful precursors for various C-C bond formations. Honer-Wadswo
Stereoselective Alkyne Hydrohalogenation by Trapping of Transfer Hydrogenation Intermediates
Das, Manas,Kaicharla, Trinadh,Teichert, Johannes F.
, p. 4926 - 4929 (2018/08/24)
A catalytically generated vinylcopper complex, the reactive intermediate of a copper(I)-catalyzed alkyne transfer hydrogenation, can be trapped by commercially available halogen electrophiles. In this manner, internal alkynes can stereoselectively be hydrohalogenated to the corresponding vinyl chlorides, bromides, and iodides.
