1448348-67-1Relevant academic research and scientific papers
A new synthesis of benzo[b]thiophene-2-thiolates and their derivatives via base-promoted transformation of 4-(2-mercaptophenyl)-1,2,3-thiadiazoles
Teplyakov, Fedor S.,Vasileva, Tatiana G.,Petrov, Mikhail L.,Androsov, Dmitry A.
supporting information, p. 4038 - 4041 (2013/09/02)
A reaction of 4-(2-mercaptophenyl)-1,2,3-thiadiazoles with an oxidant in the presence of 1.1 equiv of base afforded good yields of benzo[4,5]thieno[3,2- d][1,2,3]thiadiazoles via the intramolecular oxidative nucleophilic substitution of a hydrogen (ONHS) pathway. The reaction of 4-(2-mercaptophenyl)-1,2,3- thiadiazoles in the presence of ≥2 equiv of base gave 2-mercaptobenzo[b] thiophenes via an anionic ring-opening/ring-closure pathway.
