945454-01-3

Upstream product

• 23082-50-0 2'-chloro-5'-nitroacetophenone 
• 4114-31-2 ethylhydrazine carboxylate 

Downstream Products

• 945454-02-4 4-(2-chloro-5-nitrophenyl)-1,2,3-thiadiazole 
• 1448348-61-5 4-(2-(methylthio)-5-nitrophenyl)-1,2,3-thiadiazole 
• 1448348-60-4 N-(4-mercapto-3-(1,2,3-thiadiazol-4-yl)phenyl)acetamide 
• 1448348-59-1 4-amino-2-(1,2,3-thiadiazol-4-yl)benzenethiol 
• 1448348-67-1 1,2-bis(4-nitro-2-(1,2,3-thiadiazol-4-yl)phenyl)disulfane 
• 1448348-65-9 2-((2,4-dinitrophenyl)thio)-5-nitrobenzo[b]thiophene 
• 1448348-66-0 3-(2,4-dinitrophenyl)-2-((2,4-dinitrophenyl)thio)-5-nitrobenzo[b]thiophene 
• 1448348-75-1 2-((5-acetamidobenzo[b]thiophen-2-yl)thio)-N-(4-methoxyphenyl) acetamide 
• 1448348-74-0 N-(2-(benzylthio)benzo[b]thiophen-5-yl)acetamide 
• 1448348-72-8 N-(4-methoxyphenyl)-2-((5-nitrobenzo[b]thiophen-2-yl)thio)acetamide 
• 1448348-71-7 2-(benzylthio)-5-nitrobenzo[b]thiophene 

Relevant academic research and scientific papers

A convenient synthesis of benzo[b]chalcogenophenes from 4-(2-chloro-5-nitrophenyl)-1,2,3-chalcogenadiazoles

An unusual base-promoted transformation of readily available 4-(2-chloro-5-nitrophenyl)-1,2,3-thia- and selenadiazoles affords a convenient approach toward benzo[b]thiophenes and benzo[b]selenophenes.

In Vitro Activity of Organochalcogen Compounds: II. Cytotoxic Effect of 2-Aminobenzo[b]thiophenes Against K562 and HeLa Tumor Cell Lines

Abstract: In vitro antitumor activity of some benzo[b]thiophenes with a tertiary amino group in the second position was studied against erythroleukemia (K562) and cervical carcinoma (HeLa) cell lines.

A convenient approach towards 2- and 3-aminobenzo[b]thiophenes

Reaction of 1-(2-chloro-5-nitrophenyl)ethanone via Willgerodt-Kindler route with primary or secondary amines and sulfur allows a simple, efficient one-pot synthesis of 3-aminobenzo[b]thiophenes. Base-catalyzed transformation of 4-(2-chloro-5-nitrophenyl)-