1448530-83-3

Upstream product

• 1177255-31-0 bromotyrosinol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1448530-84-4 (S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol 
• 1448530-92-4 (1S,3S)-ethyl 8-acetoxy-2-(2-(benzyl(tert-butoxycarbonyl)-amino)acetyl)-3-(((tert-butyldimethylsilyl)oxy)methyl)-7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 
• 1448530-95-7 (1S,3S)-ethyl 2-(2-(benzyl(tert-butoxycarbonyl)amino)acetyl)-8-hydroxy-3-(hydroxymethyl)-7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 
• 1448530-96-8 (1S,3S)-ethyl 2-(2-(benzyl(tert-butoxycarbonyl)amino)-acetyl)-3-formyl-8-hydroxy-7-methoxy-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate 

Relevant academic research and scientific papers

Synthetic studies on lemonomycin: Construction of the tetracyclic core

A substrate-induced stereocontrol strategy was used to gain access to the tetracyclic core of (-)-lemonomycin. An advanced intermediate was prepared from a known substituted tyrosinol through a 16-step sequence, which involved a Pictet-Spengler reaction, a [3+2] dipolar cycloaddition and an enamide hydrogenation.