1448592-58-2

Basic information

• Product Name: (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trimethoxyphenyl)methanone
• Synonyms: (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trimethoxyphenyl)methanone
• CAS NO: 1448592-58-2
• Molecular Weight: 330.168
• Mol File: 1448592-58-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trimethoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trimethoxyphenyl)methanone(1448592-58-2)
• EPA Substance Registry System: (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trimethoxyphenyl)methanone(1448592-58-2)

Safety Data

• Hazardous Substances Data: 1448592-58-2(Hazardous Substances Data)

Upstream product

• 1448592-72-0 4, 5-dichloro-N-methoxy-N-methyl-1H-pyrrole-2-carboxamide 
• 114605-54-8 2,3,4-trimethoxyphenylmagnesium bromide 
• 121639-01-8 (1H-Pyrrol-2-yl)-(2,3,4-trimethoxy-phenyl)-methanone 
• 368211-06-7 1H-pyrrole-2-carboxylic acid methoxymethylamide 
• 2199-43-1 ethyl 1H-pyrrole-2-carboxylate 

Downstream Products

• 1448592-59-3 (4,5-dichloro-1H-pyrrol-2-yl)(2,3,4-trihydroxyphenyl)methanone 

Relevant articles and documents

MCL-1 MODULATING COMPOSITIONS

The present invention relates to marinopyrrole A derivatives and pyoluteorin derivatives and methods of treatment of disorders associated with misregulation of Mcl-l, e.g., leukemia, lymphoma, multiple myeloma, melanoma, or pancreatic cancer. We describe exemplary compounds, which may be contained in pharmaceutical compositions, and their use as therapeutic agents either alone or in combination with other anti-cancer treatments, e.g., anti-Bcl- 2 agents.