1448622-37-4

Upstream product

• 941320-76-9 1-[2-(dimethylamino)phenyl]-2,2-dimethyl-1-propaone 
• 1112-54-5 vinyltriethylsilane 
• 941320-80-5 2,2-dimethyl-1-[2-(methylamino)phenyl]-1-propanone 
• 1448622-33-0 1-(2-isopropylaminophenyl)-2,2-dimethyl-1-propanone 
• 4387-36-4 2-iodobenzonitrile 
• 147531-47-3 2-(isopropylamino)benzo-nitrile 
• 938-16-9 2,2-dimethylpropiophenone 

Relevant academic research and scientific papers

Iron-Catalyzed Regioselective Anti-Markovnikov Addition of C-H Bonds in Aromatic Ketones to Alkenes

We report here on a C-H alkylation reaction, in which the coupling of aromatic ketones with alkenes proceeds in the presence of only a simple Fe(PMe3)4 catalyst. The anti-Markovnikov addition of ortho C-H bonds in various ketones occurs with excellent regioselectivity under relatively mild reaction conditions. A strikingly wide variety of alkenes can be used for this reaction, and the high-yielding anti-Markovnikov addition of aromatic C-H bonds to enol ethers was achieved for the first time using this catalyst system.

Ruthenium-catalyzed reductive deamination and tandem alkylation of aniline derivatives

We developed two new catalytic transformations of anilines via oxidative addition of CeN bonds to ruthenium centers. One is ruthenium-catalyzed reductive deaminatoindeamination of N-alkylated oacylanilines. The other one is catalytic coupling of N-alkylated o-acylanilines with olefins giving orthoalkylated aromatic ketones via CeN bond cleavage. This reaction involves a ruthenium hydride species as an intermediate, formed after b-hydride elimination from the ruthenium amide species.