144864-49-3Relevant academic research and scientific papers
Synthesis of fluorinated chirons: Stereoselective oxirane formation by reaction of diazomethane on 1-fluoro-3-arylsulfinyl-2-propanone and ring opening by selected nucleophiles
Arnone, Alberto,Bravo, Pierfrancesco,Frigerio, Massimo,Salani, Giuliana,Viani, Fiorenza,Zappala, Carmela,Cavicchio, Giancarlo,Crucianelli, Marcello
, p. 8289 - 8310 (1995)
(R)-1-fluoro-3-[(4-methylphenyl)sulfinyl]-2-propanone (1) reacts with diazomethane affording (S)-2-(fluoromethyl)-2-{[(R)-(4-methylphenyl)sulfinyl]methyl}oxirane (2) as the main product. The influence of reaction conditions (solvent, temperature) on the c
A new versatile fluorinated C4 chiron
Arnone, Alberto,Bravo, Pierfrancesco,Cavicchio, Giancarlo,Frigerio, Massimo,Marchetti, Valeria,Viani, Fiorenza,Zappala, Carmela
, p. 5609 - 5612 (2007/10/02)
Optically pure 2-(fluoromethyl)-2-[(4-methylphenylsulphinyl)methyl]oxirane has been obtained in good yield and with high d.e. by reacting diazomethane with optically pure 1-fluoro-3-(4-methylphenylsulphinyl)propan-2-one. Regio- and stereo-selective openin
