Synthesis of fluorinated chirons: Stereoselective oxirane formation by reaction of diazomethane on 1-fluoro-3-arylsulfinyl-2-propanone and ring opening by selected nucleophiles

DOI: 10.1016/0040-4020(95)00430-G

Source and publish data:

Tetrahedron p. 8289 - 8310 (1995)

Update date:2022-07-30

Topics:

Authors:

Arnone, Alberto

Bravo, Pierfrancesco

Frigerio, Massimo

Salani, Giuliana

Viani, Fiorenza

Zappala, Carmela

Cavicchio, Giancarlo

Crucianelli, Marcello

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00430-G

(R)-1-fluoro-3-[(4-methylphenyl)sulfinyl]-2-propanone (1) reacts with diazomethane affording (S)-2-(fluoromethyl)-2-{[(R)-(4-methylphenyl)sulfinyl]methyl}oxirane (2) as the main product. The influence of reaction conditions (solvent, temperature) on the c

Full text of DOI:10.1016/0040-4020(95)00430-G

Products guided by the article

Product name:(S)-1-(benzylamino)-3-fluoro-2-(<(R)-(4-methylphenyl)sulfinyl>methyl)-2-propanol

Cas No:144864-49-3

R&D Labs maybe for 144864-49-3

Cerametek Materials（ShenZhen）Co., Ltd.

Contact:+86-755-2324.2554

Address:A3-#9, YongChuan Street, Suite 501
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

website:http://www.czyys.com

Contact:0086-519-88802789

Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
SHENYANG COMEBOARD TECHNOLOGY CO., LTD

Contact:+86-24-25724626

Address:Room2210,Tianbao International Building,No.8-1 Weigong South Street,Tiexi District,Shenyang,China
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
BOC Sciences

website:https://www.bocsci.com/

Contact:1-631-485-4226

Address:Ramsey Road

Relevant to this article

Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3β pathways

Doi:10.1039/c6md00467a
(2017)
Dimethyl (2-Furyl)-N-(2-Methoxyphenyl)Aminomethylphosphonate Induces Apoptosis in Esophageal Squamous Cancer Cells. Structure Versus Activity of its Selected Analogs

Doi:10.1080/10426507.2014.965821
(2015)
Expeditious synthetic approach and photophysical properties of fluorescent benzimidazo[1,2-d]dibenzo[b,f][1,4]diazepine derivatives

Doi:10.1039/c2ra22527a
(2013)
Studies toward the generation of functionalized quaternary carbon centers relying on wittig and wittig-still allylic ether anionic transpositions

Doi:10.1021/jo401488y
(2013)
Catalyst-free click cascade functionalization of unsaturated-bond- containing polymers using masked-ketene-tethering nitrile N-oxide

Doi:10.1016/j.polymer.2013.06.020
(2013)
Synthesis and properties of new (Phosphinoylmethyl)pyridine N-oxides

Doi:10.1002/zaac.201300099
(2013)

Article Doi