1448640-50-3Relevant academic research and scientific papers
Studies on the chemical behavior of the novel 6,8-dibromo-7- hydroxychromone-3-carboxaldehyde towards some carbon nucleophilic reagents
Ibrahim, Magdy A.,Ali, Tarik E.,El-Kazak, Azza M.,Mohamed, Amira M.
, p. 1075 - 1086 (2013/06/05)
A novel 6,8-dibromo-7-hydroxychromone-3-carboxaldehyde (4) was prepared by the Vilsemier-Haack formylation of 3,5-dibromo-2,4-dihydroxy acetophenone (3). The chemical reactivity of carboxaldehyde 4 was studied towards some carbon nucleophiles as cyclic and acyclic active methylene nucleophiles and also 1,3-C,N- and 1,3-C,C-binucleophiles as a route to achieve ring transformation to produce a variety of heterocyclic systems. Structures of the newly synthesized products have been deduced on the basis of elemental analysis and spectral data.
