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CAS

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1448695-64-4

4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1448695-64-4 Structure

  • Basic information

    1. Product Name: 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine
    2. Synonyms: 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine
    3. CAS NO:1448695-64-4
    4. Molecular Formula:
    5. Molecular Weight: 261.735
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1448695-64-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(1448695-64-4)
    11. EPA Substance Registry System: 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(1448695-64-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1448695-64-4(Hazardous Substances Data)

1448695-64-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1448695-64-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,8,6,9 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1448695-64:
(9*1)+(8*4)+(7*4)+(6*8)+(5*6)+(4*9)+(3*5)+(2*6)+(1*4)=214
214 % 10 = 4
So 1448695-64-4 is a valid CAS Registry Number.

1448695-64-4Relevant articles and documents

Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides

Kle?ka, Martin,Slavětínská, Lenka Po?tová,Tlou??ová, Eva,D?ubák, Petr,Hajdúch, Marián,Hocek, Michal

supporting information, p. 576 - 580 (2015/04/27)

A series of 7-phenylsulfanyl- or 7-(2-thienyl)sulfanyl-7-deazapurine bases bearing diverse substituents at position 6 was prepared through C-H sulfenylation of 6-chloro-7-deazapurine followed by cross-coupling or nucleophilic substitutions. The corresponding ribonucleosides (as thia-analogues of known nucleoside cytostatics) were prepared by glycosylation of 6-chloro-7-arylsulfanyl-7-deazapurines followed by the same transformations at position 6. The 7-thienylsulfanyl-7-deazapurine bases 2b-2h exerted micromolar cytostatic activities, whereas the nucleosides did not show significant biological effects. This journal is

Direct C-H sulfenylation of purines and deazapurines

Kle?ka, Martin,Pohl, Radek,?ejka, Jan,Hocek, Michal

supporting information, p. 5189 - 5193 (2013/08/23)

A general method for Cu-catalyzed C-H sulfenylation of purines, 7-deaza- and 9-deazapurines with aryl- or alkyldisulfides has been developed. In purines, the reaction occurs at position 8, in 7-deazapurines at position 7 and in 9-deazapurines at position 9, leading to new interesting arylsulfanyl derivatives of purine or deazapurine bases. The resulting 8-arylsulfanylpurines undergo Liebesking-Srogl coupling with arylstannanes or boronic acids, whereas the (arylsulfanyl)deazapurines are not reactive under these conditions.

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