1448706-79-3

Basic information

• Product Name: N-benzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol
• Synonyms: N-benzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol
• CAS NO: 1448706-79-3
• Molecular Weight: 403.519
• Mol File: 1448706-79-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol(1448706-79-3)
• EPA Substance Registry System: N-benzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol(1448706-79-3)

Safety Data

• Hazardous Substances Data: 1448706-79-3(Hazardous Substances Data)

Upstream product

• 23147-58-2 glycolaldehyde dimer 
• 61190-10-1 N-benzyl-N-(2,2-diethoxyethyl)amine 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 

Downstream Products

• 94914-96-2 1-benzyloxymethyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; hydrochloride 
• 1448706-86-2 N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol 
• 147624-55-3 4-(1-(N-(2,2-diethoxyethyl)amino)-2-(benzyloxy)ethyl)-1,2-dimethoxybenzene 
• 1448706-85-1 N,O-dibenzyl-N-(2,2-diethoxyethyl)-2-(3,4-dimethoxyphenyl)glycinol 

Relevant articles and documents

Synthesis of calycotomine and N-methylcalycotomine using a petasis reaction-pomeranz-fritsch-bobbitt cyclization sequence

The use of aminoacetaldehyde acetals as the amine components in the one-step, three-component Petasis reaction followed by the Pomeranz-Fritsch- Bobbitt cyclization has been shown to be a convenient and simple method for the synthesis of tetrahydroisoquinoline alkaloids. Using this method two alkaloids, calycotomine and N-methylcalycotomine hydrochlorides, have been prepared in 61% overall yield.