1448710-90-4Relevant academic research and scientific papers
Hydantoin based inhibitors of MMP13 - Discovery of AZD6605
De Savi, Chris,Waterson, David,Pape, Andrew,Lamont, Scott,Hadley, Elma,Mills, Mark,Page, Ken M.,Bowyer, Jonathan,Maciewicz, Rose A.
, p. 4705 - 4712 (2013)
Piperidine ether and aryl piperazine hydantoins are reported as potent inhibitors of MMP13. A medicinal chemistry campaign focused on replacing the reverse hydroxamate zinc binding group associated with historical inhibitors with a hydantoin zinc binding
