1448806-52-7Relevant articles and documents
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis
Ferrins, Lori,Rahmani, Rapha?l,Sykes, Melissa L.,Jones, Amy J.,Avery, Vicky M.,Teston, Eliott,Almohaywi, Basmah,Yin, JieXiang,Smith, Jason,Hyland, Chris,White, Karen L.,Ryan, Eileen,Campbell, Michael,Charman, Susan A.,Kaiser, Marcel,Baell, Jonathan B.
, p. 450 - 465 (2013/10/01)
A whole organism high-throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei led to the recent discovery of several novel compound classes with low micromolar activity against this organism and without appreciable cytotoxici