1448855-91-1

Basic information

• Product Name: N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-[2-oxo-2-(p-tolylthio)ethyl]-4-{1-methyl-1H-imidazole-2-carboxamido}-1H-2-pyrrolyl)carboxamido]-1H-2-pyrrolecarboxamide
• Synonyms: N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-[2-oxo-2-(p-tolylthio)ethyl]-4-{1-methyl-1H-imidazole-2-carboxamido}-1H-2-pyrrolyl)carboxamido]-1H-2-pyrrolecarboxamide
• CAS NO: 1448855-91-1
• Molecular Weight: 604.733
• Mol File: 1448855-91-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-[2-oxo-2-(p-tolylthio)ethyl]-4-{1-methyl-1H-imidazole-2-carboxamido}-1H-2-pyrrolyl)carboxamido]-1H-2-pyrrolecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-[2-oxo-2-(p-tolylthio)ethyl]-4-{1-methyl-1H-imidazole-2-carboxamido}-1H-2-pyrrolyl)carboxamido]-1H-2-pyrrolecarboxamide(1448855-91-1)
• EPA Substance Registry System: N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-[2-oxo-2-(p-tolylthio)ethyl]-4-{1-methyl-1H-imidazole-2-carboxamido}-1H-2-pyrrolyl)carboxamido]-1H-2-pyrrolecarboxamide(1448855-91-1)

Safety Data

• Hazardous Substances Data: 1448855-91-1(Hazardous Substances Data)

Upstream product

• 106-45-6 para-thiocresol 
• 30148-21-1 ethyl 1-methyl-1H-imidazole-2-carboxylate 
• 913960-95-9 1-Methyl-4-[(4-nitro-1H-pyrrole-2-carbonyl)-amino]-1H-pyrrole-2-carboxylic acid (3-dimethylamino-propyl)-amide 
• 78486-14-3 3-(1-methyl-4-aminopyrrole-2-carbonylamino)propyldimethylamine 
• 65361-30-0 N-[3-(dimethylamino)propyl]-1-methyl-4-nitro-1H-pyrrole-2-carboxamide 
• 20485-43-2 1-methyl-2-imidazolecarboxylic acid 
• 115592-72-8 2-Bromthioessigsaeure-S-(p-tolyl)ester 

Relevant articles and documents

Toward encoding reactivity using double-stranded DNA. Sequence-dependent native chemical ligation of DNA binding polyamides

The coupling reaction between distamycin-related polyamides equipped with cysteine and thioester groups can be accelerated in the presence of double-stranded (ds) oligonucleotides with selected sequences. While the coupling reaction of reactive partners containing three pyrrole units is accelerated by dsDNAs containing ATTTTA or ATGTTA sites, the heterodimeric coupling between a tripyrrole and a polyamide equipped with two pyrroles and one imidazole, is accelerated by the latter DNA, but not by the other containing the A/T rich tract. These differences can be exploited for selecting preferred coupling pairs from a mixture of reactive monomers; therefore the reaction outcome depends on the instructions provided by the dsDNA sequence.