14489-76-0Relevant academic research and scientific papers
A novel fluorescent chemosensor for Cu(II) in aqueous solution based on a β-aminobisphosphonate receptor
Kamila, Sukanta,Callan, John F.,Mulrooney, Ray C.,Middleton, Moira
, p. 7756 - 7760 (2007)
A novel β-aminobisphosphonate receptor has been combined with naphthalene in the fluorophore-spacer-receptor format of a typical photoinduced electron transfer (PET) based sensor. The sensor was synthesised in two steps by first reacting aminomethylnaphth
Asymmetric Ir-catalyzed hydrogenation of 4-R-1,3-dihydro-2H-1,5-benzodiazepin-2-ones using a novel phosphoramidite ligand
Lyubimov,Sokolovskaya,Mikhel,Birin,Davankov
, p. 1429 - 1434 (2019/08/12)
A novel chiral phosphoramidite ligand, (Sa)-2-[N-ethyl-N-(1-naphthylmethyl)amino]-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepane, was obtained and tested in Ir-catalyzed asymmetric hydrogenation of a series of 4-R-1,3-dihydro-2H-1,5-benzodiaze
Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H- pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance
Giordanetto, Fabrizio,Wallberg, Andreas,Ghosal, Saswati,Iliefski, Tommy,Cassel, Johan,Yuan, Zhong-Qing,Von Wachenfeldt, Henrik,Andersen, Soren M.,Inghardt, Tord,Tunek, Anders,Nylander, Sven
supporting information, p. 6671 - 6676,6 (2012/12/12)
Structure-based evolution of the original fragment leads resulted in the identification of 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2- methylmorpholin-4-yl]-1H-pyrimidin-2-one, (S)-21, a potent, selective phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor with favourable in vivo antiplatelet effect. Despite its antiplatelet action, (S)-21 did not significantly increase bleeding time in dogs. Additionally, due to its enhanced selectivity over p110α, (S)-21 did not induce any insulin resistance in rats.
Amine derivatives and fungicides containing the same
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, (2008/06/13)
Amine derivatives having the general formula (I): STR1 wherein X is selected from the group consisting of STR2 wherein Q is oxygen, sulfur or nitrogen atom, and STR3 wherein Q is as above; Y is selected from the group consisting of STR4 R1 is hydrogen atom or an alkyl group; R2 is hydrogen atom or an alkyl group; R3 is hydrogen atom, a halogen atom or an alkyl group; R4 is hydrogen atom, an alkyl group, a cycloalkyl group, a halogenated alkyl group or a halogen atom; R5 is hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, nitro group or hydroxy group; R5 is attached to an arbitrary position of X, and R3 or R4 is attached to an arbitrary position of Y. The amine derivatives (I) are useful as fungicides.
