1449-09-8

Basic information

• Product Name: 24-methylene cycloartanol
• Synonyms: 24-methylene cycloartanol;(9β)-24-Methylene-9,19-cyclolanostan-3β-ol;24-Methylene-9β,19-cyclolanostan-3β-ol;24-Methylenecycloartan-3β-ol;4,4,14α-Trimethyl-9β,19-cyclo-5α-ergost-24(28)-en-3β-ol
• CAS NO: 1449-09-8
• Molecular Formula: C₃₁H₅₂O
• Molecular Weight: 440.74398
• Mol File: 1449-09-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 512.7 °C at 760 mmHg
• Flash Point: 226.4 °C
• Appearance: /
• Density: 1 g/cm³
• Vapor Pressure: 1.18E-12mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 24-methylene cycloartanol(CAS DataBase Reference)
• NIST Chemistry Reference: 24-methylene cycloartanol(1449-09-8)
• EPA Substance Registry System: 24-methylene cycloartanol(1449-09-8)

Safety Data

• Hazardous Substances Data: 1449-09-8(Hazardous Substances Data)

Usage

Uses

24-Methylenecycloartan-3-ol (CAS# 1449-09-8) is a cyclized intermediate from 2,3-oxidosqualene to the steroid skeleton along the biosynthetic pathway of the phytosterols. It also has a chemotherapeutic importance, such as for antihyperlipemia.

InChI:InChI=1/C31H52O/c1-20(2)21(3)9-10-22(4)23-13-15-29(8)25-12-11-24-27(5,6)26(32)14-16-30(24)19-31(25,30)18-17-28(23,29)7/h20,22-26,32H,3,9-19H2,1-2,4-8H3/t22-,23-,24+,25+,26+,28-,29+,30-,31+/m1/s1

Upstream product

• 67-56-1 methanol 
• 21238-33-5 Cycloartenol 
• 469-36-3 24-methylenecycloarthanol trans-ferulate 
• 2845-03-6 ¹⁴C-acetic acid 
• 469-39-6 cycloeucalenol 

Downstream Products

• 25692-13-1 cyclobranol 
• 58801-00-6 24-methyl-5α-lanosta-8,24-dien-3β-ol 
• 92121-70-5 isocyclosadol 
• 92121-70-5 (23E)-cyclosadol 
• 92216-67-6 (23Z)-24-methyl-5α-lanosta-8,23-dien-3β-ol 
• 92216-66-5 (23E)-24-methyl-5α-lanosta-8,23-dien-3β-ol 
• 1449-08-7 24-methylene-9,19-cyclolanostan-3-one 
• 76236-10-7 24S-ethyl-9β,19-cyclolanost-25-ene-3β-ol 
• 469-39-6 cycloeucalenol 

Relevant articles and documents

DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS

Compounds having a cyclolanostane skeleton such as 9,19-cyclolanostan-3-ol and 24-methylene-9,19-cyclolanostan-3-ol are used as an active ingredient of a drug and food or drink for improving pancreatic functions.

Conformational Analysis of Cycloartenol, 24-Methylenecycloartanol and Their Derivatives

A conformational analysis of cycloartenol, 24-methylenecycloartenol and their derivatives was carried out in the solution and the solid state by an NMR study and X-ray crystallographic analysis, respectively.Complete assignments of the 1H NMR spectra of these compounds were made in order to elucidate the conformation involving the ring system and side chain.Rings A to C had a chair-halfchair-boat conformation, and the side chain had a zig-zag conformation.